Gastrointestinal Involvement in Langerhans Cell Histiocytosis: Computerized Tomography Findings.

Gastrointestinal Involvement in Langerhans Cell Histiocytosis: Computerized Tomography Findings

Cutaneous Langerhans cell histiocytosis with gastrointestinal involvement treated with dabrafenib

LCH: Langerhans cell histiocytosis INTRODUCTION Langerhans cell histiocytosis (LCH) is a rare disorder characterized by an abnormal clonal proliferation of histiocytes, with adult-onset LCH accounting for an estimated 30% of cases. The clinical spectrum of LCH varies widely, from asymptomatic singleorgan involvement to severe and potentially fatal multisystem disease. Although cutaneous lesions...

Langerhans cell histiocytosis

Introduction: Langerhans cell histiocytosis (LCH), which was previously known as histiocytosis X, refers to a group of lesions that stimulate uncontrolled proliferation of cells. The purpose of this case was to report and describe a LCH case with mandibular bone involvement in a 2.5-year-old boy. Case reports: A 2.5 years old boy with LCH of mandibular jaw who has been treated by surgical inter...

[Isolated conjunctival involvement in Langerhans cell histiocytosis].

CASE REPORT A 43-year-old woman referred for a hyperemic node in the inferior conjunctival fornix. No improvement was observed after 10 days of antibiotic and anti-inflammatory topical treatment, so biopsy-extirpation was performed. Histopathological and immunohistochemical findings suggested the diagnosis of Langerhans cell histiocytosis (LCH). No findings of extraocular manifestations were sh...

Skeletal involvement in Langerhans cell histiocytosis

UNLABELLED Langerhans cell histiocytosis (LCH) represents a disorder characterised by an abnormal accumulation of histiocytes in miscellaneous tissues. The bone is commonly affected, especially the flat bones, the spine and the long bones. Some lesions in children such as a "vertebra plana" or a solitary lytic lesion of the skull may be suggestive for LCH, whereas others can be confused with a ...